The manipulation of liquids in microchannels, of which widths are several tens or hundreds um, is becoming a central technology in chemical, biological, and medical applications owing to the possibility of simple and high throughput analysis in nucleic acid analysis, enzyme assays and immunoassays. Especially capillary electrophoresis (CE) on a microchip where a capillary of conventional CE is replaced by a microchannel or microchannels on a plate made of glass, polydimethylsiloxane (PDMS) and polymethylmethacrylate (PMMA) has been attracted by many researchers because of fast analysis, simplicity, small reagent consumption and selectively handling fluidic materials in order to deliver many kinds of chemical and biochemical components through a complex network. We believe our DBMA-100 will be helpful for you to realize lab-on-a-chip technology in your laboratories.

A simple and flexible benchtop microfluidic analysis system, DBMA-100 provides users with a variety of functions. Microchips of various sizes can be used without any modification or with minor change. You can also change channel disign, well position, chip material, and so on according to your applications. Digital Bio Technology supplies total solutions for microfluidics as well as a microfluidic analyzer. We recommend you to consult the PMM service center of Digital Bio Technology, to make microchips of your own design.

Small loading volumes of DBMA-100 can save your money for reagents.
Only several uL of reagents in an experiment is sufficient.

The multi-channel high voltage power supply (DBHV-100) makes user-designed experiments possible by providing up to 8 independent output channels.

The laser-induced fluorescence detection system of DBMA-100 supplies high sensitivity and selectivity to your experiments.

The XY-mechanical stage with large strokes of DBMA-100 make it possible to investigate microfluidic phenomena at any point of your microchips.

The Z-precision stage is a convenient tool for you to precisely align your microchips.

CCD images make you examine the states of your microchips and their microchannels in your eyes without a microscope.

Simple and convenient control software helps you to easily design your experiments.

 

 

 

 

 

 

1. Light sources

 

 

You can choose a green laser or a red laser as a light source (factory setting). It is difficult and costly to change the kind of the laser after making the main system even if it is possible. Please carefully determine this option before ordering.

 

Green laser : diode-pumped solid-state laser (10 mW, 532 nm)

Red laser : diode laser (10 mW, 635 nm)

 

 

 

2. Detector

 

The fundamental optical detector of DBMA-100 is a PMT for laser-induced fluorescence detection.

 

 

 

3. Full strokes of mechanical stages for alignment

 

X-stage: 110 mm

Y-stage: 32.5 mm

Z-stage: 10 mm

 

The XY-stage moves the chip plate, and the Z-stage moves the objective lens, that is, the optical module.

 

 

 

4. Electrodes

 

Up to 8 independent electrodes for high voltage are available.
Each channel supplies 5 kV and 0.2 mA at maximum.

 

 

 

5. Data acquisition system

 

A data acquisition board is used to acquire fluorescence signal from a PMT, and an analog output board is used to control a high voltage power supply.

 

Data acquisition board: 16 bit analog-to-digital conversion

Analog output board: 12 bit digital-to-analog conversion

 

 

 

6. Size and weight

 

Main system
- Size : 450 mm (W) × 340 mm (L) × 405 mm (H)
- Weight : ~10 kg

High voltage power supply
- Size : standard 19-inch rack size (435 mm (W) × 415 mm (L) × 135 mm (H))
- Weight : ~2 kg

 

 

 

 

 

DNA fragments separation (Figure1)

 

PCR product identification

Peptides and proteins separation

Enzyme immunoassays

Chemiluminescence detection

Microfluidic (Dye) manipulation (Figure2)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Brochure Download                     DBMA-100Catalog.pdf